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Tobramycin is an antibiotic that is inhaled into the lungs using a nebulizer. Tobramycin inhalation is used to treat lung infections in patients with cystic fibrosis.
tobramycin is for use in adults and children who are at least 6 years old.
Tobramycin inhalation may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
You should not use tobramycin if you are allergic to tobramycin or similar antibiotics (amikacin, gentamicin, kanamycin, neomycin, paromomycin, streptomycin).
Tell your doctor if you have ever had:
It is not known whether tobramycin inhalation will harm an unborn baby. However, a medicine similar to tobramycin caused irreversible hearing damage in babies whose mothers took that medicine during pregnancy.
Tell your doctor if you are pregnant or plan to become pregnant. Having cystic fibrosis during pregnancy may increase the risk of premature birth. The benefit of treating cystic fibrosis may outweigh any risks to the baby.
If you breastfeed while using tobramycin, watch the baby for signs of diarrhea, blood in the stools, or a fungal diaper rash with white patches on the skin.
Tobramycin is not approved for use by anyone younger than 6 years old.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Tobramycin is inhaled into the lungs with the use of a nebulizer or an inhaler device. Do not swallow the medicine by mouth.
Use only the inhaler device provided with your medicine.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
Tobramycin is given in a treatment cycle of 28 days on and 28 days off. Follow your doctor's dosing instructions very carefully. Keep using tobramycin on this schedule, even if you feel fine.
Use your doses at regular intervals of 12 hours apart but not less than 6 hours apart.
If you use other inhaled medicines, or if you perform chest physiotherapy to remove mucus from the lungs, use these other treatments first before using your tobramycin dose.
Do not use tobramycin inhalation solution if it looks cloudy or has particles in it. Call your pharmacist for new medicine.
Store tobramycin ampules in the refrigerator between 36 and 46 degrees Fahrenheit (2 and 8 degrees Celsius).
If refrigeration is not available, store the ampules at cool room temperature for up to 28 days. Protect from light. The solution may become darker in color at room temperature, but this should not affect the quality of the medicine.
Store Tobi Podhaler capsules in their original blister pack at room temperature away from moisture and heat. Remove a Tobi Podhaler capsule from the blister pack only when you are ready to load it into your inhaler device.
Use the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 6 hours. Do not use two doses at one time.
Do not mix tobramycin solution with dornase alfa (Pulmozyme) in the nebulizer.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur.
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects.
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect tobramycin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.